| Selected Publications |
- Irie, K., Gotoh, Y., Yashar, B., Errede, B., Nishida, E., Matsumoto, K. Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase. Science 265, 1716-1719 (1994).
- Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., Matsumoto, K. Identification of a member of the MAPKKK family as a potential mediator of TGF-b signal transduction. Science 270, 2008-2011 (1995).
- Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y, Ueno, N., Irie, K., Nishida, E., Matsumoto, K. TAB1: an activator of the TAK1 MAPKKK in TGF-b_signal transduction. Science 272, 1179-1182 (1996).
- Ichijo, H., Nishida, E., Irie, K., Dijke, P., Saitoh, M., Moriguchi, T., Takagi, M., Matsumoto, K., Miyazono, K., Gotoh, Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathway. Science 275, 90-94 (1997).
- Kurokawa, M., Mitani, K., Irie, K., Matsuyama, T., Takahashi, T., Chiba, S., Yazaki, Y., Matsumoto, K., Hirai, H. The oncoprotein Evi-1 represses TGF-b signalling by inhibiting Smad3. Nature 394, 92-96 (1998).
- Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., Matsumoto, K. The kinase TAK1 can activate the NIK-IkB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 398, 252-256 (1999).
- Meneghini, M., Ishitani, T., Carter, C., Hisamoto, N., Ninomiya-Tsuji, J., Thorpe, J., Matsumoto, K., Bowerman, B. MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in C. elegans. Nature 399, 793-797 (1999).
- Ishitani, T., Ninomiya-Tsuji, J., Nagai, S., Nishita, M., Meneghini,M., Barker, N., Waterman, M., Bowerman, B., Clever,H., Shibuya, H., Matsumoto, K. The TAK1-NLK-MAPK related pathway antagonizes signalling between b-catenin and the transcription factor TCF. Nature 399, 798-802 (1999).
- Adachi-Yamada, T., Fujimura-Kamada, K., Nishida, Y., Matsumoto, K. Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing. Nature 400, 166-169 (1999).
- Nishiwaki, K., Hisamoto, N., Matsumoto, K. A metalloprotease disintegrin that controls cell migration in Caenorhabditis elegans. Science 288, 2205-2208 (2000).
- Kondo, T., Wakayama, T., Naiki, T., Matusmoto, K., Sugimoto, K. Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science 294, 867-870 (2001).
- Kim, D. H., Feinbaum, R., Alloing, G., Emerson, F. E., Garsin, D. A., Inoue, H., Tanaka-Hino, M., Hisamoto, N., Matsumoto, K., Tan, M-W., Ausubel, F. M. A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297, 623-626 (2002).
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