Field of Research

Interdisciplinary area of single molecule nanobiology and biophysics / cell biology / neuroscience. Current interests include the mechanisms of signal transduction in the cell membrane, the dynamic structure and function of the plasma membrane including the membrane skeleton and rafts, the mechanisms for the formation and plasticity of synapses and for the development of neuronal polarity, and development of single molecule technologies that can be applied to the studies of living cells.
Selected Publishments

    1)      Nakada,C: Ritchi,K.; Oba,Y.; Nakamura,M; Hotta,Y.; Iino,R.; Kasai,R.; Yamaguchi,K.; Fujiwara,T.; Kusumi,A.  Accumulation of anchored proteins forms membrane diffusion barriers as neurons develop polarization. Nat.Cell Biol.5, 2003,626-632

    2)      Ike,H.; Kosugi,A.; Iino,R.; Hirano,H.; Fujiwara,T.; Ritchi,K.; Kusumi,A.  Mechanism of Lck recruitment to the T-cell receptor cluster as studied by single molecule fluorescence video imaging, Chem.Phys.Chem.4, 2003,620-626

    3)      Subczynski,W.K.; Pasenkiewicz-Gierula,M.; McElhaney,R.N.; Hyde,J.S.; Kusumi,A.  Molecular dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine memberanes containing ransmembrane ƒ¿-helical peptides with alternating leucine, alanine residues. Biochemistry 42, 2003,3939-3948

    4)      Ritchie, K.; Kusumi,A.  ``Single particle tracking image microscopy``.  Methods In Enzymol. 360, ``Biophotonics``, G. Marriott and Ian Parker, editors. San Diego, Academic Press, 2003, 618-634.(invited review article)

    5)      Kusumi,A.; Koyama-Honda,I.; Suzuki,K. ``Molecular Dynamics and Interactions for Creation of Stimulation-Induced Stabilized Rafts from Small Unstable Steady-State-Rafts``. Traffic 5, 2004, 213-230. (invited review article)