Field of Research

Molecular mechanism of biological timing in vertebrates

Selected Publications
  • Yasuo S, Nakao N, Ohkura S, Iigo M, Hagiwara S, Goto A, Ando H, Yamamura T, Watanabe M, Watanabe T, Oda SI, Maeda KI, Lincoln G, Okamura H, Ebihara S,Yoshimura T. Long day suppressed expression of type 2 deiodinase gene in the
    mediobasal hypothalamus of the Saanen goat, a short day breeder: Implication for seasonal window of thyroid hormone action on reproductive neuroendocrine axis. Endocrinology (in press)

  • Yasuo S, Watanabe M, Nakao N, Takagi T, Follett BK, Ebihara S, Yoshimura T.The reciprocal switching of two thyroid hormone activating and inactivating enzyme genes is involved in the photoperiodic gonadal response of Japanese quail. Endocrinology 146, 2551-2554 (2005)

  • T. Yamamura, K. Hirunagi, S. Ebihara, T. Yoshimura. Seasonal morphological changes in the neuro-glial interaction between GnRH nerve terminals and glial endfeet in Japanese quail. Endocrinology 145:4264-4267 (2004).

  • M. Watanabe, S. Yasuo, T. Watanabe, T. Yamamura, N. Nakao, S. Ebihara, T. Yoshimura. Photoperiodicregulation of type 2 deiodinase in Djungarian hamster: Possible homologies between avian and mammalian photoperiodic regulation of reproduction. Endocrinology 145: 1546-1549 (2004).

  • S. Yasuo, M. Watanabe, A. Tsuakda, T. Takagi, M. Iigo, K. Shimada, S. Ebihara, T. Yoshimura. Photoperiodic phase specific light induction of Cry1 gene in the pars tuberalis of Japanese quail. Endocrinology 145:1612-1616 (2004).

  • T. Yoshimura, S. Yasuo, M. Watanabe, M. Iigo, T. Yamamura, K. Hirunagi, S. Ebihara. Light induced T4 to T3@conversion regulates photoperiodic response of gonads in birds. Nature 426: 178-181 (2003).

  • S. Yasuo, M. Watanabe, N. Okabayashi, S. Ebihara T. Yoshimura. Circadian clock genes and photoperiodism: Comprehensive analysis of clock gene expression in the mediobasal hypothalamus, the suprachiasmatic nucleus, and the pineal gland of Japanese quail under various light schedules. Endocrinology 144: 3742-3748 (2003)

  • N. Hayashi, S. Yasuo, S. Ebihara, T. Yoshimura. Expression of IKKƒ¿ mRNA in the suprachiasmatic nucleus and circadian rhythms of mice lacking IKKƒ¿. Brain Res  933: 217-221 (2003).

  • N. Okabayashi, S. Yasuo, M. Watanabe, T. Namikawa, S. Ebihara, T. Yoshimura. Ontogeny of circadian clock gene expression in the pineal and the suprachiasmatic nucleus of chick embryo. Brain Res  990: 231-234(2003)

  • T. Yoshimura, Y. Yokota, A. Ishikawa, S. Yasuo, N. Hayashi, T. Suzuki, N. Okabayashi, T. Namikawa, S. Ebihara. Mapping quantitative trait loci affecting circadian photosensitivity in retinally degenerate mice. J Biol Rhythm 17: 512-519 (2002).

  • T. Yoshimura, S. Yasuo, Y. Suzuki, E. Makino, Y. Yokota, S. Ebihara. Identification of the suprachiasmatic nucleus in birds. Am J Physiol 280: R1185-1189 (2001).

  • T. Yoshimura, Y. Suzuki, E. Makino, T. Suzuki, A. Kuroiwa, Y. Matsuda, T.Namikawa,  S. Ebihara. Molecular analysis of avian circadian clock genes. Mol Brain Res 78: 207-215 (2000).