Field of Research

Molecular Cell Biology
Selected Publications

  • K. Yamano, Y. Yatsukawa, M. Esaki, A. E. A Hobbs, R. E. Jensen, and T. Endo: Tom20 and Tom22 share the common signal recognition pathway in mitochondrial protein import. J. Biol. Chem. 283: 3799-3807 (2008)

  • T. Yoshihisa, C. Ohshima, K. Yunoki-Esaki, and T. Endo: Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae
    Genes Cells     12, 285-297 (2007)

  • T. Momose, C.Ohshima, M.Maeda, T.Endo: Structural basis of functional cooperation of Tim15/Zim17 with yeast mitochondrial Hsp70.a. EMBO Rep. 8, 664-670 (2007)

  • T. Saitoh, M. Igura, T. Obita, T. Ose, R. Kojima, K. Maenaka, T. Endo, and D. Kohda: Tom20 recognizes mitochondrial presequences through dynamic equilibrium among multiple bound states. EMBO J. 26, 4777-4787 (2007)

  • Y. Tamura, Y. Harada, K. Yamano, K. Watanabe, D. Ishikawa, C. Ohshima, S. Nishikawa, H. Yamamoto, and T. Endo: Identification of Tam41 mainteining integrity of theTim23 protein translocator complex in mitochondria. J. Cell Biol. 174, 615-623 (2006)

  • T. Sato, M. Esaki, J. M. Fernandez, and T. Endo: Comparison of the protein unfolding pathways between mitochondrial protein import and AFM measurements. Proc. Natl. Acad. Sci. USA 102, 17999-18004 (2005)

  • M. Esaki, T. Kanamori, S. Nishikawa, I. Shin, P. G. Schultz, and T. Endo: Tom40 protein import channel binds to non-native proteins and prevents their aggregation.  Nature Struct. Biol. 10, 988-994 (2003)

  • H. Yamamoto, M. Esaki, T. Kanamori, Y. Tamura, S. Nishikawa, and T. Endo :Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes. Cell 111, 519-528 (2002)

  • Nishikawa, S. W. Fewell, Y. Kato, J. L. Brodsky, and T. Endo: Molecular chaperones in the yeast ER maintain the solubility of proteins for retro-translocation and degradation. J. Cell Biol. 153, 1061-1070 (2001)

  • A. Kawai, S. Nishikawa, A. Hirata, and T. Endo: Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yerast cells. J. Cell Sci. 114, 3565-3574 (2001)

  • K. Nakatsukasa, S. Nishikawa, N. Hosokawa, K. Nagata, and T. Endo : Mnl1p, an ƒ¿-mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J. Biol. Chem. 276, 8635-8638 (2001)

  • Y. Abe, T. Shodai, T. Muto, K. Mihara, H. Torii, S. Nishikawa, T. Endo, D. Kohda: Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20. Cell 100, 551-560 (2000)

  • M. Esaki, T. Kanamori, S. Nishikawa,  and T. Endo : Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochorme b2 import pathway. Proc. Natl. Acad. Sci. USA 96, 11770-11775 (1999)

  • T. Kanamori, S. Nishikawa, I. Shin, P. G. Schultz, and T. Endo:       Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking. Proc. Natl. Acad. Sci. USA 94, 485-490, (1997)

  • M. Nakai, A. Goto, T. Nohara, D. Sugita, and T. Endo: Identification of the SecA protein homolog in pea chloroplasts and its possible involvement in thylakoidal protein transport. J. Biol. Chem. 269, 31338-31341 (1994)